Programming

Metabolic programming is the adaptation to nutritional insults during early development which may permanently alter physiology or metabolism of the offspring later in life, even if the stimuli are not present any more. Epigenetic mechanisms such as DNA methylation contribute to this programming.

Programing by fetal sex

PI Silvija Tokic

Fetal sex influences in utero development in both uncomplicated pregnancies and pregnancies with sub-optimal outcomes. Furthermore, susceptibility to adult complex diseases i.e. cardiovascular diseases originates in utero, commonly secondary to the effects of placental dysfunction - the concept known as fetal programing.

Programming endothelial function

PI Ursula Hiden

Metabolic programming is the adaption to nutritional insults during early development which may permanently alter physiology or metabolism of the offspring, even if these stimuli are not present any more.

Prenatal HMOs: Roles in priming the fetus for long term consequences?

PI Evelyn Jantscher-Krenn

Evidence from studies in human milk is amounting that exposure to HMOs in early life may have long term benefits for the health of the breastfed child. HMOs might ameliorate risk for overweight, allergies, and metabolic diseases.