Normal pregnancy

During pregnancy, the placenta, an organ of fetal origin, is essential for fetal development and growth. The placenta anchors the fetus, produces bioactive factors that temporally adapt maternal metabolism to pregnancy, and performs nutrient transport to the fetus. We are intrigued how these essential functions, e.g. placentation, metabolic adaptions and transport, are regulated by maternal and fetal factors.

Lipases and Lipid Signaling

PI Christian Wadsack

Lipid metabolites are well established modulators of inflammation and therefore pharmacological modulation of their biosynthesis and degradation are promising approaches to anti-inflammatory drug treatment.